creatinine measured by a modified jaffe method on an abbott architect c16000  (Abbott Laboratories)

Journal: Antioxidants

Article Title: Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome

doi: 10.3390/antiox11050901

Figure Lengend Snippet: Oxidative stress and inflammatory plasma markers of participants according to the median values of adherence Mediterranean Diet Pattern.

Article Snippet: All the results of urine biochemical parameters were normalized by the levels of creatinine measured by a modified Jaffe method on an Abbott ARCHITECT c16000 (Abbott Diagnostics, Lake Bluff, IL, USA) in the clinical laboratory of Son Espases Hospital (Spain).

Techniques: Clinical Proteomics

Journal: Clinical Mass Spectrometry

Article Title: A simplified, rapid LC-MS/MS assay for serum and salivary creatinine

doi: 10.1016/j.clinms.2018.11.004

Figure Lengend Snippet: Method comparison between a kinetic alkaline picrate assay (Abbott Architect c16000 analyser) and the LC-MS/MS assay using 20 anonymised surplus serum samples. (A) Deming regression analysis of LC-MS/MS creatinine plotted against the Abbott Jaffe creatinine result. (B) Bland Altman (difference) plot illustrating the agreement between the two methods. Average bias and 95% limits of agreement are shown.

Article Snippet: The percentage change in measured creatinine compared to the unspiked sample was calculated for both creatinine methods. (B) Fifteen patient samples with high concentrations of endogenous glucose were analysed for creatinine by both assays and the % difference between the Abbott Jaffe method and the LC-MS/MS assay is shown for each sample.

Techniques: Comparison, Liquid Chromatography with Mass Spectroscopy

Journal: Clinical Mass Spectrometry

Article Title: A simplified, rapid LC-MS/MS assay for serum and salivary creatinine

doi: 10.1016/j.clinms.2018.11.004

Figure Lengend Snippet: Effect of glucose on measured creatinine. (A) Pooled serum was spiked with glucose to provide a range of concentrations. Glucose was measured using a hexokinase enzymatic assay and creatinine was analysed using both the Abbott Architect Jaffe method and by LC-MS/MS. The percentage change in measured creatinine compared to the unspiked sample was calculated for both creatinine methods. (B) Fifteen patient samples with high concentrations of endogenous glucose were analysed for creatinine by both assays and the % difference between the Abbott Jaffe method and the LC-MS/MS assay is shown for each sample.

Article Snippet: The percentage change in measured creatinine compared to the unspiked sample was calculated for both creatinine methods. (B) Fifteen patient samples with high concentrations of endogenous glucose were analysed for creatinine by both assays and the % difference between the Abbott Jaffe method and the LC-MS/MS assay is shown for each sample.

Techniques: Enzymatic Assay, Liquid Chromatography with Mass Spectroscopy

Journal: Clinical Mass Spectrometry

Article Title: A simplified, rapid LC-MS/MS assay for serum and salivary creatinine

doi: 10.1016/j.clinms.2018.11.004

Figure Lengend Snippet: Effect of bilirubin on measured creatinine. Five serum samples were spiked with bilirubin in DMSO or with DMSO alone, and the bilirubin concentration and icteric index were measured on an Abbott Architect analyser. Abbott Jaffe creatinine and LC-MS/MS creatinine values are plotted against icteric index (A, C) or measured bilirubin (B, D).

Article Snippet: The percentage change in measured creatinine compared to the unspiked sample was calculated for both creatinine methods. (B) Fifteen patient samples with high concentrations of endogenous glucose were analysed for creatinine by both assays and the % difference between the Abbott Jaffe method and the LC-MS/MS assay is shown for each sample.

Techniques: Concentration Assay, Liquid Chromatography with Mass Spectroscopy